Knowledge of protein folding is important because proteins must assume the correct three-dimensional structure to function properly. Misfolding may inactivate a protein or make it toxic. A new approach has allowed JILA scientists to capture the protein’s folding steps at microsecond resolution.
By showing how the folding of membrane proteins can be studied in more detail, JILA scientists have shown how researchers may better understand previously obscure biophysical processes related to diseases such as neurodegeneration and cancer.
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New Article in GEN
“The increased complexity was stunning. Better instruments revealed all sorts of hidden dynamics that were obscured over the last 17 years when using conventional technology.”
— Tom Perkins, Ph.D., the leader of the team at JILA