metabolites

Viewing posts tagged metabolites

03 Apr 2017

Cancer subtypes could be distinguished using metabolomic analysis

By Jay Goth

The emerging field of metabolomics has the potential to contribute significantly to biomarker discovery and cancer. While other techniques, such as DNA sequencing, have led to significant advances in precision oncology, metabolomics has yet to make its mark on the field.

New methods of using metabolomics as a tool for clinical cancer research and care were presented at the 2nd Annual Biomarker Conference by CureMatch, developer of a decision support platform for combination therapy in cancer.
See the full story at Oncology Central.

19 Jan 2017

The Missing Link that Binds the Microbiome with Human Health

By Jay Goth

The human microbiome is large and complex. It is thought that there are as many indigenous microbes in your body as there are other cells. The only way to understand how the microbiome’s presence affects the body at any given time is through studying the comprehensive or global metabolome—the collection of metabolites that the microbiome and host produces and interacts with. Metabolites are the microbiome’s language.

human entrails under X-rays. 3d render.


In short, trying to resolve the link between the microbiome and human health without looking at the metabolome is like trying to predict a married couple’s compatibility without observing how they communicate with each other.

Since a metabolomics approach allows scientists to examine all the small molecules in our body, including hormones, amino acids, co-factors, neurotransmitters, and other compounds, it gives us a shot at understanding every step of disease etiology, from gene to phenotype.

Read the entire article in GEN

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