The growth in cancer genomics has been one of the most exciting scientific and technological developments in cancer research, spurring significant advances in patient care and laying the groundwork for many future advances.
In the year since it was launched, the National Cancer Institute’s Genomic Data Commons (GDC) has collected and harmonized a vast quantity of cancer genomics data—more than 4.5 petabytes—which has been fundamental in the recent progress against cancer and holds the promise for continued improvement in our ability to diagnose, treat, and care for patients.
Now, as a data-analysis system, the GDC is taking major steps toward engaging the broader research community and encouraging further collaboration and data sharing. They recently introduced a new program – Data Analysis, Visualization, and Exploration Tools, an online, open-access cancer research resource called DAVE.
DAVE is a new web interface for exploring and analyzing cancer genomic data, in real time, online, without the need to download or process the data.
DAVE provides an unprecedented level of flexibility in exploring the data. Researchers can create custom cohorts for analysis by selecting patients with particular altered genes or other relevant biological and clinical features. And researchers are no longer bound to analyzing patients only in the context of their original project cohorts—a powerful innovation given the recent evidence that a tumor’s molecular features are far more accurate and informative for cancer subtyping than tissue of origin or histology.
Another step forward for precision medicine! For the details, visit the National Cancer Institute.