genomic

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13 Jun 2017

Promise of Gene Therapy Being Realized?

By Jay Goth

Gene therapy has finally made it over the hump. After decades of research and some devastating setbacks, major technical hurdles have been overcome, opening up the long-anticipated promise of this field. A new approval has buoyed interest, pipelines are bubbling with new candidates and big investments are being made.

News about promising gene therapies in the clinic is sprouting up all the time. Scientific challenges remain considerable, though, and pricing will clearly be one of the biggest hurdles for gene therapies going forward.

“Today’s challenges are all around building a viable business model”

— Geoff MacKay, President and CEO of AvroBio

For the complete article at BioPharma Dive, click here.

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Exciting BioPharma News

13 Jun 2017

Predictive Gene Expressions

By Jay Goth

Qiagen has reported that the company and Bristol-Myers Squibb will explore the use of NGS to develop gene expression profiles as predictive or prognostic tools for use with several BMS immuno-oncology therapies. The companies also plan to enter into a further agreement to develop diagnostic products using the jointly developed profiles to expand the use of NGS technology with other BMS immuno-oncology therapies.

“Greater precision in the treatment of cancer may enable faster decision making to identify which patient populations are most likely to derive benefit from our immuno-oncology agents.”

–Fouad Namouni, Bristol-Myers Squibb

This development is an example of the trend towards companion diagnostics, in which the use of predictive biomarkers identify individually-based therapies.
Read the announcement here.

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