lipidomics

Viewing posts tagged lipidomics

08 Mar 2017

Genes in Fat Cells May Contribute to Dangerous Diseases

By Jay Goth

A sweeping international effort is connecting the dots between genes in our fat cells and our risk for obesity and cardiometabolic diseases such as heart disease and type 2 diabetes. The researchers have identified approximately 90 genes found in fat that could play important roles in such diseases – and could be targeted to develop new treatments or cures.

“Genetic factors do not work in isolation – they work in a holistic way, so I think that these kind of studies that we are publishing are key to understanding what’s happening in human populations.”

— Mete Civelek of the University of Virginia School of Medicine
Read the entire article at Science Blog

06 Feb 2017

Lipidomics – an important ‘omic modality

By Jay Goth

Lipidomics is a new frontier of ‘omics research and offers much promise for new-generation biomarkers for common complex phenotypes. According to a white paper from the Computational and Structural Biology Laboratory, Division of Biological Sciences and Engineering, Netaji Subhas Institute of Technology, Dwarka, India, traditional clinical markers for prognosis of hyperlipidemic individuals are inadequate to forecast or diagnose cardiac events.

The white paper describes attributes from lipidomics that can help identify risk of future cardiac events and other areas of concern. It concludes that additional studies are required to establish the range of normal and disease levels of the identified lipids in different populations and conditions and that lipidomics deserves greater research attention from the biomarker and precision medicine research communities.

You can read an abstract of the report here. Lipidomics is one of the many ‘omics modalities being investigated by Blueprint Bio.

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